The Japanese Knotweed component of Neuromodin™ has been shown to be neuroprotective and improve physiologic markers and behavioral metrics in a number of animal studies. Neuromodin™ has been especially formulated to draw upon these benefits. We are hopeful that these results will translate to humans in improving learning and memory, and in stabilizing behavior.

In a series of studies conducted in an animal model of autism spectrum disorder (ASD), a highly bioavailable form of emodin demonstrated improvements in outcomes related to learning, memory, and enhanced sociability. With Neuromodin™, we hope that these improvements will translate to individuals with ASD-like symptoms.

Neuromodin™ is a proprietary formulation that contains Japanese Knotweed extract and piperine extract. Japanese Knotweed has been used in traditional Chinese medicine for thousands of years and has not been associated with serious side effects. The limited human studies investigating the effects of oral supplementation with Japanese Knotweed did not report adverse side effects.

The regulations in Europe specifically address botanical species containing hydroxyanthracene derivatives, and the substances considered for risk assessment are those found in specific plants like Rheum palmatum, Cassia senna, Rhamnus frangula, Rhamnus purshiana, and Aloe barbadensis. The regulations do not mention Japanese Knotweed (Polygonum cuspidatum), and Japanese Knotweed is the supplement source in Neuromodin™.

Japanese Knotweed may be available for purchase from certain retail sites. However, these formulations generally have poor bioavailability and are not designed or dosed for use to enhance cognition and behavior. In Neuromodin™, we have developed a proprietary, highly bioavailable formula of Japanese Knotweed that has been specifically designed to be easier for individuals to take and to maximize any potential benefits in learning, memory, and behavior*.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

No. The components of Neuromodin™ may share some similar mechanisms of action with the pharmaceutical agent suramin, but the two products are chemically different and they should not be considered interchangeable.

Unfortunately, at the moment, we are unable to process returns for Neuromodin™. We regret any inconvenience this may cause.

We do provide international shipping. Please contact us for shipping rates based on your location and to place an order.

Certainly, you can decrease the water amount, but please be aware that this could lead to a stronger taste. It is important to strike a balance so that you are able to swallow the mixture with ease.

Certainly, you are welcome to mix Neuromodin™ with orange juice, apple juice, ice cream, yogurt, and more. Given its mixed berry flavor, incorporating it into a yogurt or juice with a similar taste profile would be a particularly delightful option!